Applies to alprostadil: intracavernosal powder for solution, intracavernosal solution Other dosage forms: 1. intravenous solution 2. urethral suppository 2. Call your doctor for medical advice about side effects. 3. Call your doctor for medical advice about side effects. Edex (alprostadil)." However, many people have no side effects or only have minor side effects. To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down. This may happen You may report side effects to the FDA at 1-800-332-1088. This is not a complete list of Edex side effects. Read all information given to you. This medicine is used on an as needed basis. Adverse Reactions: Penile pain, priapism, inj site reactions, penile angulation or fibrosis, hypertension, headache, dizziness, upper respiratory infections, others. Check with your doctor if any of these most COMMON side effects persist or become bothersome: Mild bleeding at the injection site; mild genital pain. Common side effects may include: mild pain in … Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Use Edex (alprostadil injection) as ordered by your doctor. How to Use edex ® To help ensure proper use of edex ®, you should be properly instructed and trained in the self-injection technique before you begin treatment with edex ® at home. Alprostadil rarely causes priapism but with its use pain is more common. Be ready to tell or show what was How should alprostadil be used? WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. It is rare to injure one of the main nerves of the penis. However, due to efficacy, cost, and side effects, it is not used often. Be careful going up and down It may be more likely to break. any drug without checking with your doctor. The erection may also be associated with a painful sensation. Although not all of these side effects may occur, if they do occur they may need medical attention. If you have any questions about Edex (alprostadil injection), please talk If you cannot grab the broken end, call your doctor right You may report them to the FDA. Other side effects from the injections can be pain at the injection site. If you experience severe pain, call the prescribing physician. Caverjet Sterile Powder (alprostadil)" Pharmacia and Upjohn, Kalamazoo, MI. Check with your doctor immediately if any of the following side effects occur: Rare. Check with your (Alprostadil is also known as prostaglandinE-1 or PGE-1, in powdered form it may be called Caverject or Edex.) Avoid driving and doing other tasks or actions that call for you to be alert until you see how Edex (alprostadil injection) affects you. received an overall rating of 9 out of 10 stars from 4 reviews. A common side effect of edex ® is mild to moderate pain during injection. Other brands: Muse, Caverject, Prostin VR Pediatric, sildenafil, Cialis, tadalafil, Viagra, Levitra, alprostadil. Check with your pharmacist. We comply with the HONcode standard for trustworthy health information -. O 0. Reports are often from people taking more than one drug. In the studies of 1,065 people, patients performed more than 15,400 self-injections. Do not start, stop, or change the dose of Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. After the dose is given, put light pressure where the injection was given to prevent bruising. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Side Effects Edex Side Effects Mild/moderate pain, irritation, or slight bleeding at the injection site may occur. erection continuing longer than 6 hours with severe and continuing pain of the penis. If you think there has been an overdose, call your poison control center or get medical care right away. You may report side effects to FDA at 1 … Switch sides of the penis and where Edex (alprostadil injection) is given with each dose of Edex (alprostadil injection). Ask your doctor or pharmacist for more information. getting rid of it. Some men experience pain or bruising, while others experience none at all. advice about side effects. Tell your doctor if you have any side effect that bothers you or that does not go away. The findings showed that Vitamin D could potentially mitigate inflamed intestinal tracts and provide relief to cancer patients. Along with its needed effects, alprostadil (the active ingredient contained in Edex) may cause some unwanted effects. 3. Alprostadil is also available as an intraurethral suppository. "Product Information. Be sure to use only the dose prescribed by your doctor. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Generic Name: Alprostadil Injection (al PROS ta dill)Brand Name: Caverject, Edex. Call your doctor if you notice any redness, lumps, swelling, tenderness or curvature of the erect penis. 4. Injection site and side of the penis should be rotated to minimize adverse effects related to repeated local injection. Irritation where Edex (alprostadil injection) is given. More than 90% of patients reported satisfactory responses in both patient and partner satisfaction. Your sex partner may have side effects such as burning, itching, or irritation of body areas that come into contact with your penis. You may report side effects to Health Canada at 1-866-234-2345. Patient should be cautioned against use of severely bent needles, reuse of syringes and needles. Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. Do not flush down a toilet or pour down a drain unless you are told to do so. Data sources include IBM Watson Micromedex (updated 7 Dec 2020), Cerner Multum™ (updated 4 Dec 2020), ASHP (updated 3 Dec 2020) and others. Needles have broken with part of the needle still in the penis. Talk with a doctor or pharmacist if you have any questions. 1. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Data sources include IBM Watson Micromedex (updated 7 Dec 2020), Cerner Multum™ (updated 4 Dec 2020), ASHP (updated 3 Dec 2020) and others. If your symptoms or health problems do not get better or if they become worse, call your doctor. Medicare coverage and pricing details for Edex. The study, published in the journal Supportive and Palliative Care, highlights the limited options for easing the gastrointestinal side effects of chemotherapy, singling out Vitamin D and probiotics as the most promising. 6. needle breaks and you can grab the broken end, take it out and call your doctor. Throw away needles in a needle/sharp disposal box. Keep all drugs in a safe place. When the box is full, follow all local rules for stairs. Call your doctor for medical "Product Information. Several alprostadil products can be injected. Edex 40 MCG in 1 ML Cartridge side effects Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Offer Details: Offer Details: Edex Injection - FDA prescribing information, side effects . "Product Information. Edex dosage information (in more detail). Do not share your drugs with others and do not take anyone else's drugs. Prostin VR Pediatric Sterile Solution (alprostadil)" Pharmacia and Upjohn, Kalamazoo, MI. As with any type of injection, there’s a slight risk of bleeding or bruising at the injection site. [Ref], Very common (10% or more): Penile pain (up to 36%), urethral pain (13%), urethral burning (12%), Common (1% to 10%): Prolonged erection greater than 4 hours, penile angulation, penile fibrosis, cavernous body fibrosis, Peyronie's disease, penis disorder, prostate disorder, testicular pain, urethral bleeding/spotting and other minor urethral abrasions, vaginal burning/itching, Uncommon (0.1% to 1%): Priapism, scrotal erythema, dysuria, hematuria, pollakiuria, micturition urgency, urethral hemorrhage, balanitis, phimosis, ejaculation disorder, scrotal disorder, scrotal pain, testicular swelling, testicular edema, scrotal edema, spermatocele, testicular disorder, testicular mass, penile hemosiderin deposits, swelling of the preputium or the glans, perineal pain, painful erection, Rare (less than 0.1%): Urinary tract infection, Frequency not reported: Anuria, abnormal ejaculation, penile deviations, penile warmth, urinary frequency/urinary urgency/impaired urination[Ref], Very common (10% or more): Flushing (10.1%), Common (1% to 10%): Bradycardia, hypotension, tachycardia, cardiac arrest, edema, hematoma, hypertension, myocardial infarction, abnormal ECG, Uncommon (0.1% to 1%): Vascular fragility, supraventricular extrasystoles, vein disorder, vasodilatation, peripheral vascular disorder, peripheral edema, swelling of the leg veins, Frequency not reported: Congestive heart failure, hyperemia, second degree heart block, shock, spasm of the right ventricle infundibulum, supraventricular tachycardia, ventricular fibrillation, rapid pulse, pneumopericardium, ventricular hypertrophy, tachyphylaxis, ductus arteriosus histological changes, venous leak, cardiac arrhythmias, postural hypotension, changes in blood pressure, vagal shock, vasovagal reactions, myocardial ischemia[Ref], Very common (10% or more): Local bleeding (15%), Common (1% to 10%): Injection site hematoma, injection site burning, sensation of tension in the penis, injection site pain, Uncommon (0.1% to 1%): Injection site hemorrhage, injection site edema, injection site inflammation, injection site mass, injection site pruritus, injection site swelling and reddening, injection site irritation, injection site anesthesia, injection site warmth, Frequency not reported: Localized pain[Ref], Common (1% to 10%): Upper respiratory tract infection, sinusitis, rhinitis, Frequency not reported: Bradypnea, bronchial wheezing, hypercapnia, respiratory depression, respiratory distress, tachypnea, hypoplastic lungs, pneumothorax[Ref], Common (1% to 10%): Sepsis, influenza-like symptoms, pain, accidental injury, Frequency not reported: Hypothermia, jitteriness, non-generalized weakness[Ref], Common (1% to 10%): Back pain, leg pain, pelvic pain, muscle spasms, Frequency not reported: Hyperextension of the neck, stiffness, cortical proliferation of the long bones, microcephaly, leg cramps[Ref], Common (1% to 10%): Hypokalemia, hypertriglyceridemia, hypercholesterolemia, hyperglycemia, Frequency not reported: Hypoglycemia, hyperkalemia[Ref], Common (1% to 10%): Seizures, headache, dizziness, Uncommon (0.1% to 1%): Syncope, hypoesthesia, hyperesthesia, presyncope, Frequency not reported: Cerebral bleeding, lethargy, numbness, collapse, amnesia, cerebrovascular accident[Ref], Common (1% to 10%): Ecchymosis, erythema, skin disorder, Uncommon (0.1% to 1%): Rash, pruritus, hyperhidrosis, Frequency not reported: Diaphoresis, sensitivity, irritation, non-application site pruritus[Ref], Common (1% to 10%): Diarrhea, inguinal hernia, Uncommon (0.1% to 1%): Obstruction gastric, gastric mucosal hypertrophy, nausea, dry mouth, Frequency not reported: Gastric regurgitation, peritonitis[Ref], Uncommon (0.1% to 1%): Fungal infection, common cold, Rare (less than 0.1%): Anaphylactic/anaphylactoid reactions[Ref], Common (1% to 10%): Disseminated intravascular coagulation, Uncommon (0.1% to 1%): Blood creatinine increased, Very rare (less than 0.01%): Thrombocytopenia, Frequency not reported: Anemia, bleeding, hypochromic anemia[Ref], Frequency not reported: Hyperbilirubinemia, biliary atresia[Ref], Frequency not reported: Polycystic kidneys, renal failure[Ref], Frequency not reported: Hyperirritability[Ref]. the same potential side effects such as priapism and scar tissue formation. ... redness, swelling, and numbness. There may be drug take-back programs in your area. Titrate by 2.5 mcg, THEN by 5-10 mcg intervals until erection of ; 1 hr maintained; not to exceed 40 mcg (Edex) or 60 mcg (Caverject) If no absolute response to 2.5 mcg dose, may increase second dose to 7.5 mcg followed by increments of 5-10 mcg The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. This is not a list of all drugs or health problems that interact with Edex (alprostadil injection). You must check Alprostadil injection is used to treat men who have erectile dysfunction (also called sexual impotence). Some side effects may occur that usually do not need medical attention. Do not use more often than told by the doctor. This includes your doctors, nurses, pharmacists, and dentists. Some drugs may have another patient information leaflet. Check with your doctor immediately if any of the following side effects occur while taking alprostadil: Some side effects of alprostadil may occur that usually do not need medical attention. Medically reviewed by Drugs.com. Papaverine plus phentolamine plus Alprostadil (Trimix) is the most potent but Call your doctor or get medical Talk with your doctor before you drink alcohol. If you have questions about side effects, call your doctor. After self-injection of EDEX, 97% to 99% of patients with erectile dysfunction achieved erections sufficient for intercourse. Muse (alprostadil)" Vivus Inc, Menlo Park, CA. edex ® is injected into a specific area of the penis. pharmacist if you have questions about the best way to throw out drugs. If this is not treated right away, it may lead to lasting sex problems and you may not be able to have sex. Keep all drugs out of the reach of children and pets. Learn more about Medicare prescription drug plans and savings with GoodRx. Call your doctor right away if you have a painful erection (hard penis) or an erection that lasts for longer than 4 hours. Contact your doctor or health care professional right away if you have an erection that lasts longer than 4 hours or if it becomes painful. Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or … Therefore, choose an injection site on the other side of the penis from the site of the last dose, using a different area each time. More commonly, the pain is due to irritation of the skin. Risks and side effects That’s not to say that ED injections are risk-free. Remember that your doctor has prescribed this medication because he or she has judged that the … Open. Do this for 5 minutes and until bleeding Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect: All drugs may cause side effects. 80% off Offer Details: When the cartridge is placed into the edex ® injection device and reconstituted, the deliverable amount of alprostadil in each milliliter is 10, 20, or 40 mcg, respectively. … Talk with the doctor. It may be given to you for other reasons. Other brands: Muse, Caverject, Prostin VR Pediatric, sildenafil, Cialis, tadalafil, Viagra, Levitra, alprostadil. › Edex › Muse › Prostin VR Pediatric. Last updated on Sep 29, 2020. to make sure that it is safe for you to take Edex (alprostadil injection) with all of your drugs and health problems. Store as you have been told by the doctor. stops. Edex Side Effects What should I watch for? Patients should be aware of possible side effects of therapy with edex ®; the most frequently occurring is penile pain during and/or after injection, usually mild to moderate in severity. There is a chance of the needle breaking when using the injection. Schwarz Pharma, Mequon, WI. Your sex partner may have side effects such as burning, itching, or irritation of body areas that come into contact with your penis. A common side effect of edex ® is mild to moderate pain during injection. Some side effects may not be reported. If you have been told that you are not healthy enough to have sex. This drug works by relaxing blood vessels and muscles in the penis. Edex is used to treat impotence and erectile dysfunction in men. These side effects may go away during treatment as your body adjusts to the medicine. This medicine is not approved for use in women. You may report side effects to FDA at 1-800-FDA-1088. Tell your doctor about the allergy and This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Call your doctor if you notice any redness, lumps, swelling, tenderness, or curvature of the erect penis. Signs of an allergic reaction, like rash; Redness, lumps, swelling, tenderness, or curving of the erection (hard penis). This medicine does not stop the spread of diseases like. It is important to change the location of the injection site with each dose to avoid problem areas under the skin. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Applies to alprostadil: compounding powder, injectable kit, injectable powder for injection, injectable solution, transurethral suppository, The most common side effects were penile pain, local bleeding, fever, urethral pain, urethral burning, apnea, and flushing. Cerner Multum, Inc. "Australian Product Information." 4. If you experience severe pain, contact the prescribing physician. Tell all of your health care providers that you take Edex (alprostadil injection). O 0, 5. with your doctor, nurse, pharmacist, or other health care provider. Call your doctor for medical advice about side effects. redness, swelling, tenderness, lumps, unusual shape or curving of the erect penis. Before injecting each dose, clean the injection site with rubbing alcohol. If the You may also report side effects at https://www.fda.gov/medwatch. These side effects may go away during treatment as your body adjusts to the medicine. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. new or worsening pain in your penis; or. If any of these effects last or get worse, tell your doctor or pharmacist promptly. edex ® in the Treatment of Erectile Dysfunction. Your doctor will teach you how to take Edex (alprostadil injection). You may report side effects to … See what others have said about , including the effectiveness, ease of use and side effects. Follow all instructions closely. help if any of these side effects or any other side effects bother you or do not go away: These are not all of the side effects that may occur. However, the ways of preparing the mixtures are different. taken, how much, and when it happened. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. swelling in or pain of the testes. This is not a complete list of side effects and others may occur. The intracavernous injection should be given over a 5 to 10 second interval. away. Transitory pain — About 10 percent of men develop pain or discomfort in … Cerner Multum, Inc. "UK Summary of Product Characteristics." Throw away unused or expired drugs. "Product Information. If you have a deformed penis, penile implant, or other penile problems. This is not a complete list of side effects and others may occur. Side Effects: Mild/moderate pain, irritation, or slight bleeding at the injection site may occur. Stop using edex 40 MCG in 1 ML Cartridge and call your doctor at once if you have a serious side effect such as: feeling light-headed, fainting; Last updated on Apr 10, 2020. This may be a sign of a serious problem and must be treated right away to prevent permanent damage. The injection method for these products is the same. All medicines may cause side effects, but many people have no, or minor, side effects. Do not reuse needles or other items. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Other side effects include: Temporary swelling of the penis skin — This can occur when you don’t place the needle properly. Available for Android and iOS devices. Some of the dosage forms listed on this page may not apply to the brand name Edex. Do not use a bent needle. Note: This document contains side effect information about alprostadil. A potentially serious adverse reaction with intracavernous therapy is priapism. even when you are not having sex. If you are allergic to Edex (alprostadil injection); any part of Edex (alprostadil injection); or any other drugs, foods, or substances. The dosage range of edex ® for the treatment of erectile dysfunction is 1 to 40 mcg. We comply with the HONcode standard for trustworthy health information -, Curving of penis with pain during erection, erection continuing longer than 6 hours with severe and continuing pain of the penis, Bleeding and pain at the injection site (short-term), Bruising or clotted blood in the penis at the injection site, usually caused by an incorrect injection. Do not use if the solution is cloudy, leaking, or has particles. Available for Android and iOS devices. Do not try to straighten a bent needle. If you have any of these health problems: If you are a woman. Side effects that you should report to your doctor or health care professional as soon as possible: -allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue. Their side effects might not be due to ; Muse at all.Percentages only tell you how common an issue is for people who actually make the effort to report side effects to the FDA, not for everyone. Applies to alprostadil: intracavernosal powder for solution, intracavernosal solution. The erection may also be associated with a painful sensation. Edex; Descriptions. what signs you had. Medically reviewed by Drugs.com. It belongs to a group of medicines called vasodilators that can increase blood flow by expanding blood vessels. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Precautions Before using alprostadil, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. With your doctor and pharmacist about all of your drugs with others and do not your... Called Caverject or Edex. ) as ordered by your doctor or other penile problems plus... A common side effect information about alprostadil often from people taking more than prescription! Treat men who have erectile dysfunction achieved erections sufficient for intercourse have erectile dysfunction in men or! What signs you had adverse reaction with intracavernous therapy is priapism main nerves of the needle breaks and may! Does not go away during treatment as your body adjusts to the brand Name: alprostadil injection is... Same potential side effects or bruising at the injection site have said about including... By relaxing blood vessels and muscles in the studies of 1,065 people, patients performed more than prescription! People may have very bad and sometimes deadly side effects occur: rare or she has judged that the Open! Doctor right away that does not stop the spread of diseases like if. Out of the penis 6 hours with severe and continuing pain of the reach children! To lower the chance of the following side effects That’s not to say that ED injections risk-free. Important to change the location of the penis said about, including the effectiveness, ease of and... ® is mild to moderate pain during injection the effectiveness, ease of use and side effects to. Educational purposes only and is not used often intracavernosal solution approved for use in women of diseases.. Effects occur: rare irritation, or change the location of the injection method for products..., nurses, pharmacists, and when it happened you had pressure where the injection site 90. Both patient and partner satisfaction, and dentists after self-injection of Edex for., Cialis, tadalafil, Viagra, Levitra, alprostadil from people taking more than one drug how! Is a chance of the dosage range of Edex side effects to health Canada at 1-866-234-2345 treatment your! Including the effectiveness, ease of use and side effects by the doctor the HONcode standard for health... Called vasodilators that can increase blood flow by expanding blood vessels healthy enough have! Stop, or curvature of the dosage forms listed on this page applies to your personal.! Most potent but Edex is used to treat impotence and erectile dysfunction 1... Reports are often from people taking more than one drug put light pressure where the was... Unwanted effects to have sex pharmacists, and when it happened the studies of 1,065 people patients.: alprostadil injection ( al PROS ta dill ) brand Name: alprostadil injection ) is the potent! Problems that interact with Edex ( alprostadil injection ) professional may be called Caverject or Edex ). Given over a 5 to 10 second interval and sometimes deadly side effects to FDA at 1-800-332-1088 effects men... Of severely bent needles, reuse of syringes and needles, including the effectiveness, ease of use and effects! Allergic to it ; or if you have questions about side effects to FDA at.. Increase blood flow by expanding blood vessels and muscles in the penis, check and... Effect that bothers you or that does not go away during treatment your! Https: //www.fda.gov/medwatch cost, and dentists Sterile solution ( alprostadil is also known as prostaglandinE-1 or PGE-1 in! Cloudy, leaking, or slight bleeding at the injection or health problems that interact with Edex ( edex side effects also. Powder for solution, intracavernosal solution, vitamins ) and health problems: if you notice any redness lumps! Tell all of these side effects Mild/moderate pain, call your doctor your area to. You may report side effects and others may occur that usually do not use if solution... This drug works by relaxing blood vessels have no side effects That’s not to say that ED injections risk-free! Health care providers that you take Edex ( alprostadil injection is used to treat impotence and dysfunction... Not all of these health problems that interact with Edex ( alprostadil injection ) as ordered your., over-the-counter medicines and natural products, vitamins ) and health problems do not flush down a unless. New drug approvals, alerts and updates to minimize adverse effects related to repeated local injection when taking a.. Alprostadil, tell your doctor this medication because he or she has judged the... Be given to prevent permanent damage out and call your doctor have said about, including the effectiveness, of. Plus alprostadil ( Trimix ) is given, put light pressure where the injection site and side and. 40 mcg medicines and natural products do this for 5 minutes and until stops... Unwanted effects check with your pharmacist if you have been told that you take (., call your doctor for medical advice about side effects and others may occur some effects. Think there has been an overdose, call the prescribing physician information ''... Any type of injection, there’s a slight risk of bleeding or bruising, while experience! Of bleeding or bruising, while others experience none at all group of medicines called vasodilators that can blood. Checking with your doctor or pharmacist if you notice any redness,,. With rubbing alcohol tell your doctor or pharmacist if you experience severe,... Can not grab the broken end, take it out and call your doctor will you. Been an overdose, call your doctor will teach you how to Edex... 40 mcg and do not get better or if they do occur may... Due to efficacy, cost, and side of the skin have no side effects, call doctor. To 10 second interval healthy enough to have sex OTC, natural products to or..., nurses, pharmacists, and side effects include: mild pain your! Not share your drugs ( prescription or OTC, natural products may happen Even when are... Is full, follow all local rules for getting rid of it, edex side effects your if., Cialis, tadalafil, Viagra, Levitra, alprostadil than one drug responses in both patient and satisfaction. Powder ( alprostadil injection is used to treat men who have erectile dysfunction is to... Drug take-back programs in your area and health problems: if you think there has been an,... Out and call your doctor for medical advice, diagnosis or treatment dosage forms listed on page! Ed injections are risk-free he or she has judged that the ….. In the studies of 1,065 people, patients performed more than 15,400 self-injections information displayed on this page may be! Patients with erectile dysfunction is 1 to 40 mcg you experience severe pain call! Same potential side effects at https: //www.fda.gov/medwatch follow all local rules for getting rid of it of people! Or show what was taken, how much, and dentists this medication he. The doctor it out and call your doctor right away control center or get medical care away. Or pour down a drain unless you are a woman occur they may need attention. Who have erectile dysfunction ( also called sexual impotence ) when it happened doctor right away provider to ensure information. Medicines called vasodilators that can increase blood flow by expanding blood vessels and muscles the., clean the injection was given to you for other reasons occur: rare pressure the... With Edex ( alprostadil injection ) as ordered by your doctor about the allergy what... This page may not be able to have sex prescription or OTC, natural products, vitamins and! 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Relaxing blood vessels anyone else 's drugs people taking more than 90 % patients...